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AACE and ADA prioritize hypoglycemia risk reduction and prevention in their treatment guidelines

Minimizing the risk of both severe and nonsevere hypoglycemia is a priority. It is a matter of safety, adherence, and cost”1

“It is important to prevent hypoglycemia to reduce the risk of cognitive decline and other major adverse outcomes”2

Identifying patients with T2D and hypoglycemia risk factors is critical for effective individualized treatment3

Intensive glycemic control

Previous episodes of hypoglycemia

Renal impairment

Intensive glycemic control

Previous episodes of hypoglycemia

Renal impairment

Cognitive dysfunction

Duration of diabetes

Advanced age

Cognitive dysfunction

Duration of diabetes

Advanced age


It is important to address the risk of hypoglycemia in the elderly2

Elderly patients with diabetes have additional challenges, including higher rates of unidentified cognitive deficits

Hypoglycemic events leading to falls/fractures or hospital admissions could result in substantial costs and downstream care (eg, nursing home)

Addressing hypoglycemia is a shared responsibility

Payer

Ensure formulary options meet the needs of patients at higher risk of hypoglycemia

Align interests of medical, quality, and pharmacy

Health system

Consider hypoglycemia when establishing management guidelines for patients with diabetes

Identify patients at high risk of hypoglycemia across care delivery in screening and coding

Provider

Determine therapy options that balance efficacy and safety

Improve screening for hypoglycemic risk factors at point of care

AACE=American Association of Clinical Endocrinologists

References:

  1. Garber AJ, Abrahamson MJ, Barzilay JI, et al. Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm—2018 executive summary. Endocr Pract. 2018;24(1):91-120.
  2. American Diabetes Association. Standards of medical care in diabetes—2018. Diabetes Care. 2018;41(suppl 1):S1-S159.
  3. Yun JS, Ko SH. Risk factors and adverse outcomes of severe hypoglycemia in type 2 diabetes mellitus. Diabetes Metab J. 2016;40(6):423-432.